Keppra XR Dosage Strength Tablets to Combat Partial One-Set Seizures

Posted by: Doctor Medical  :  Category: Health, Health News, Medication

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Keppra has improved on its dosage, unveiling the Once-daily Keppra XR extended-release tablets which are now available in a new dosage strength, 750 mg. This enables doctors to simplify patients’ treatment plans by decreasing the number of tablets they take each day.

According to studies published in Epilepsy & Behavior and Neurology, patients are more likely to adhere to their medication regimen when it is taken once daily, and therefore may be more likely to reach the goal of epilepsy therapy–seizure freedom with minimal side effects.

Keppra XR was approved by the U.S. Food and Drug Administration (FDA) based on data from an international clinical study of 158 epilepsy patients with partial-onset seizures who added 1,000 mg of Keppra XR or placebo to their other epilepsy medications once daily. The study consisted of an 8-week baseline period followed by a 12-week treatment period.

  • The study showed that 10.1 percent of Keppra XR(TM) patients experienced complete partial-onset seizure freedom vs. 1.3 percent in the placebo group over the treatment period.
  • Keppra XR patients experienced a 46.1 median percent reduction in weekly partial-onset seizure frequency versus 33.4 percent in the placebo group.

Keppra XR is also available in 500 mg tablet strength. Data presented at last year’s American Epilepsy Society meeting demonstrated that taking two 750 mg levetiracetam extended-release tablets is the same as taking three 500 mg extended-release tablets.

Treatment with Keppra XR should be initiated with a dose of 1,000 mg once daily. The daily dosage may be adjusted in increments of 1,000 mg every two weeks, to a maximum recommended dose of 3,000 mg per day.

(Source) Press

Tags: american epilepsy society, baseline period, dosage, Epilepsy, epilepsy patients, food and drug, food and drug administration, food and drug administration fda, Health, increments, Keppra, levetiracetam, medication regimen, mg tablet, minimal side effects, neurology, partial onset seizures, placebo group, recommended dose, release tablets, seizure frequency, seizures, treatment, treatment period

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